Tuesday, September 25, 2012
BTI's research team, in collaboration with other centres, has published two scientific articles that deal in depth with the different biological functions that Plasma Rich in Growth Factors (PRGF®-Endoret®) carries out.
BTI's research team, in collaboration with other centres, has published two scientific articles that deal in depth with the different biological functions that Plasma Rich in Growth Factors (PRGF®-Endoret®) carries out.
In the first of them, published in the Journal of Periodontology, it is shown that PRGF®-Endoret® significantly increases the proliferation, migration and chemotaxis of cells, stimulating the main biological processes of osteoblasts in their function of bone regeneration.
On the other hand, the article published in the Journal of Biomedical Materials Research A presents the results of the research carried out on the release of growth factors from surfaces of implants bioactivated with PRGF®-Endoret®. The same article ascertains that with the use of this technique regeneration around the implant is improved. In addition, two different activators of the coagulation cascade: calcium and thrombin were tested. Calcium, in addition to avoiding an immune response, allows a greater release of platelet factors around the implant. The article highlights the importance of activating the PRGF®-Endoret® prior to its use in the bioactivation of surfaces as an increased permanence of the different growth factors on the surface is achieved, a vital aspect to accelerate osseointegration.
