What makes PRGF – ENDORET® unique | BTI Biotechnology Institute

Why use ENDORET® technology instead of other PRPs?

AUTOLOGOUS AND SAFE
- Eliminates adverse effects and incompatibility risks [1]
- Promotes natural homeostasis
- Stimulates the proliferation and migration of cells
- Encourages the body's own secretion of proteins from the extracellular matrix
OPTIMUM PLATELET CONCENTRATION
- Achieves a platelet concentration 2 to 3 times the baseline level
- Creates a balance between growth factors derived from platelets and those derived from plasma [2] [3]
REDUCED INFLAMMATORY CONTENT
- Contains insignificant amount leukocytes or inflammatory proteins [2] [4]
- Helps reduce inflammation, pain, and tissue fibrosis [5]
- Preserves the structural integrity of the fibrin matrix over time [5] [6]
CONTROLLED ACTIVATION
- Promotes the targeted release of growth factors from platelets
- Induces the polymerization of the fibrin matrix for a stable scaffold [7]
DUAL EFFECT AND BIOAVAILABILITY
- ENDORET® Technology provides a dual-action effect on tissues [8] [9]:
  
  • Immediate action: Delivers an initial impact from growth factors upon application
  • Sustained Action: The fibrin matrix acts as a natural reservoir, providing a prolonged and gradual release of factors over time
VERSATILITY
- Allows for the preparation of specific formulations tailored to diverse tissue types and clinical requirements.
SECURITY AND COMPLIANCE GUARANTEES
- All medical equipment and devices used in the closed-system ENDORET® Technology:
  
  • Have passed extensive quality controls to comply with current regulations, including endotoxin and sterility testing
  • Are manufactured from fully biocompatible materials
  • Meet all requirements for clinical medical devices as established by relevant healthcare authorities across the globe
SCIENTIFIC EVIDENCE
- The efficacy and safety of ENDORET® Technology are supported by over 250 indexed scientific publications.
TRAINING
- A wide range of training programs is available, adapted to different medical specialties, to help professionals achieve excellence in their daily clinical practice.

Information note