Wednesday, December 19, 2007
The research team headed by Dr. Eduardo Anitua (Scientific Director, BTI Biotechnology Institute) published 4 international articles of special relevance and scientific impact.
The research team headed by Dr. Eduardo Anitua (Scientific Director, BTI Biotechnology Institute) published 4 international articles of special relevance and scientific impact.
Throughout the last decade, the group of researchers led by Dr. Eduardo Anitua has made a tremendous effort in R&D, principally in two strategic areas: dental implants and regenerative medicine.
The characterization, development and optimization of a 100% autologous and biocompatible biological preparation called preparation rich in growth factors (PRGF) has caused a revolution in the acceleration of bone and soft tissue healing and regeneration. PRGF® technology, which Biotechnology Institute (BTI) pioneered, has been applied effectively in various medical disciplines such as sports lesions, dental implants, oral and maxillofacial surgery, arthroscopic and orthopedic surgery, the treatment of chronic ulcers, plastic and reconstructive surgery, ophthalmology, etc.
Likewise, BTI continually strives to enhance the surface and design of implants, studying and optimizing its biomechanical behavior as well as evaluating its efficacy and safety at the preclinical as well as the clinical level, with the only goal of improving the biosafety, predictability and therefore the therapeutic success of dental implants.
Recently, these efforts have been translated into the publication of 4 international articles of special relevance and scientific impact that demonstrate not only the therapeutic possibility of PRGF® in tissue regeneration and regenerative medicine, but also the predictability and success of BTI dental implants activated with PRGF®.
A great vision of the broad versatility of the PRGF® technology and its therapeutic possibilities are summarized in the article published in the journal Biomaterials1, the number one journal in the field of material science (impact: 5.2) and first percentile in the field of biomedical engineering. The work is included in the opinion leaders section and represents the first article of this nature published in this scientific area.
In another of the works published in the journal Trends in Pharmacological Science, there is a discussion on the importance of the spatial-temporal release of the growth factors to effectively develop and accelerate the healing processes and tissue regeneration. This article, which summarized the principal technologies designed for the controlled release of biological factors including the PRGF® technology, marks a new milestone for BTI since it represents the publication of higher scientific impact in the world bibliography that describes the potential of this type of treatment based on growth factors (impact factor: 10.3; first percentile in the field of pharmacy and pharmacology).
Also, 2 scientific articles which demonstrate the high level of biosafety, efficacy and predictability of BTI dental implants bioactivated with PRGF® were published. Of special relevance in this work, recently accepted in the Journal of Clinical Periodontology (first percentile in the field of dental/maxillofacial surgery) in which the five-year survival of nearly 6,000 BTI implants is analyzed. The importance of this work not only lies in the enormous number of implants evaluated – one of the largest described in the world literature – but also in the results of the same, which concludes that the survival of BTI dental implants was 99.2%. These results demonstrate that BTI dental implants currently provide the greatest guarantee of success and safety in the dental panorama.
Finally, it is necessary to underline that in another work similar to that published in the Journal of Periodontology, and in which the overall 5-year survival of 532 BTI short implants was examined, the results reflected an identical success rate (99.2%).This article is of special relevance for the field since it dispels existing doubts about the efficacy of short implants. In fact, BTI bioactivated, short implants offer a totally safe and predictable guarantee for patients.
The publication of these scientific works not only represents an additional stimulus in our daily research work, but above all the confirmation of a therapeutic reality that we understand is of vital importance at the social and health level, and particularly for each patient who undergoes a treatment with PRGF® or receives BTI dental implants.
Bibliografía
